蓝芳
职称与职务：研究员、博导
专业：生物医学工程、材料学、化学
邮箱地址：fanglan@scu.edu.cn
联系电话：15882134563
办公地址：四川大学望江校区生物材料楼713室
工作及教育经历
2012—至今 四川大学国家生物医学材料工程技术研究中心/生物医学工程学院，工作
2009—2012四川大学国家生物医学材料工程技术研究中心，有机化学，博士
2006—2009四川大学化学学院，绿色化学，硕士
2002—2006四川师范大学化学学院，化学，学士
长期从事纳米生物医学材料和医疗器械材料表界面等研究，包括基于蛋白质、肽段、DNA和代谢物的疾病早期诊断和预后监测，以及微环境响应的生物材料表界面改性等应用。主持包括国家自然科学基金委面上项目和青年项目、“十三五”重点研发计划项目子课题、教育部博士点项目、四川省科技计划项目，及四川大学优秀青年学者研究基金（A类）等13项。以第一作者或通讯作者发表SCI源刊论文40余篇，（包括Small、ACS Applied Materials & Interfaces、Analytical Chemistry等国际权威期刊），授权中国发明专利18件，参与编写生物材料专著1部。获四川大学“唐立新优秀学者”和四川大学“好未来优秀学者奖”。指导学生获国家级、校级“大创”项目。
研究方向
1.功能磁性纳米复合材料及疾病早期诊断；
2.新型微环境响应医疗器械智能界面的可控构筑及再生医学应用。
近五年代表性论文
[1] Bin Luo, Juan Zhou, Zhigui Li, Jiajia Song, Peng An, Huinan Zhang, Yi Chen,Fang Lan,*Binwu Ying, and Yao Wu*. Ultrasensitive DNA Methylation Ratio Detection Based on the Target-Induced Nanoparticle-Coupling and Site-Specific Base Oxidation Damage for Colorectal Cancer.Analytical Chemistry, 2022, 94, 6261-6270
[2] Bin Luo, Yujia Zhang, Peng An, Juan Zhou, Fang Lan,* Binwu Ying, and Yao Wu*.Covalent Organic Framework Nanosheets Anchored with Highly Dispersed Au Nanoparticles as a Novel Biosensor for DNA Methylation Detection.Journal of Colloid and Interface Science, 2022, 626，241-250
[3] Jia He, Bin Luo, Huinan Zhang, Zhiyu Li, Nanhang Zhu,Fang Lan*, and Yao Wu*.Liquid Surfactant-assistedSynthesis of Covalent Organic Framework Nanospheres in Water at Room Temperature.Journal of Colloid and Interface Science, 2022, 606, 1333-1339
[4] Jia He, Lingzhu Yu, Zhiyu Li, Shengdong Ba, Fang Lan* and Yao Wu*. Catalyst Regulated Interfacial Synthesis of Self-standing Covalent Organic Framework Membranes at Room Temperature for Molecular Separation.Journal of Colloid and Interface Science, 2022, doi.org/10.1016/j.jcis.2022.09.036
[5] Zhiyu Li, Yichun Gao, Peng An,Fang Lan,*and Yao Wu. Hydrophilic magnetic covalent organic frameworks for highly integrated pre-enrichment and analysis of colorectal cancer differential glycoproteomics.Materials & Design,2022, 217, 110584-110595
[6]Lingzhu Yu, Bin Luo, Xiaoxi Zhou,Yicheng Liu,Fang Lan,*and Yao Wu*. In-Situ Controllable Fabrication of Two-Dimensional Magnetic Fe3O4/TiO2@Ti3C2Tx Composites for High-Efficient Phosphopeptides Enrichment.ACS Applied Materials & Interfaces, 2021, 13, 54665-54676
[7] Bin Luo, Shuang Yan, Huinan Zhang, Juan Zhou,Fang Lan,*Binwu Ying, Yao Wu*.Metal-Organic Framework-Derived Hollow and Hierarchical Porous Multivariate Metal-Oxide Microspheres for Efficient Phosphoproteomics Analysis.ACS Applied Materials & Interfaces,2021, 13, 34762-34772
[8] Bin Luo, Jia He, Zhiyu Li,Fang Lan*,and Yao Wu*. Glutathione-Functionalized Magnetic Covalent Organic Framework Microspheres with Size Exclusion for Endogenous Glycopeptide Recognition in Human Saliva.ACS Applied Materials & Interfaces,2019, 11, 47218-47226
[9] Bin Luo, Qiang Chen, Jia He, Zhiyu Li, Lingzhu Yu,Fang Lan*,and Yao Wu*. Boronic acid-functionalized magnetic metal-organic frameworks via dual ligand strategy for highly efficient enrichment of phosphopeptides and glycopeptides.ACS Sustainable Chemistry & Engineering, 2019, 7, 6043-6052
[10]Bin Luo,MinggangYang, Peipei Jiang,Fang Lan,*and Yao Wu*,Multi-affinity sites of magnetic guanidyl-functionalized metal-organic framework nanospheres for efficient enrichment of global phosphopeptides,Nanoscale, 2018, 10, 8391-8396
