个人简介
2018.06-至今 四川大学，生物材料工程研究中心，专职博士后，助理研究员
2013.09-2017.06四川大学，生物材料工程研究中心，工学博士
2010.09-2013.07四川大学，生物材料工程研究中心，工学硕士
2006.09-2010.07四川大学，材料学院，理学学士
主要研究方向为纳米材料的合成、修饰及肿瘤诊断治疗，围绕肿瘤诊疗对载体、药物的要求，对纳米材料的合成及性质进行优化，在体内外对耐药肿瘤进行诊断和治疗。此外，基于基质材料的物理特性可调控细胞行为、诱导组织再生等性质，构建并探讨三维基质微环境中多重物理信号对细胞行为的影响研究。
研究方向
1.荧光纳米材料设计合成以及在肿瘤诊疗方面的应用
2.干细胞诱导分化
代表性论文专著
1.Chen, X.; Tang, Y.; Liu, A.; Zhu, Y.; Gao, D.; Yang, Y.; Sun, J.; Fan, H.*; Zhang, X. NIR-to-Red Upconversion Nanoparticles with Minimized Heating Effect for Synchronous Multidrug Resistance Tumor Imaging and Therapy.ACS Appl. Mater. Interfaces2018,10, 14378-14388.
2.Chen, X.; Sun, J.; Zhao, H.; Yang, K.; Zhu, Y.; Luo, H.; Yu, K.; Fan, H.*; Zhang, X. Theranostic System Based on NaY(Mn)F4:Yb/Er Upconversion Nanoparticles with multi-drug resistance (MDR) reversing ability.J. Mater. Chem. B2018,6, 3586-3599.
3.Chen, X.; Tang, Y.; Cai, B; Fan, H*. ’One-pot’ synthesis of multifunctional GSH–CdTe quantum dots for targeted drug delivery.Nanotechnology2014, 25, 235101.
4.Tang, J.; Hui, J.; Zhang, M.; Fan, H.; Rowell, N.; Huang, W.; Jiang, Y.;Chen, X.*; Yu, K.*CdS Magic-Size Clusters Exhibiting One Sharp Ultraviolet Absorption Singlet Peaking at 361 nm.Nano Res.2019,12, 1437-1444.
5.Liu, Y.; Rowell, N.; Willis, M.; Zhang, M.; Wang, S.; Fan, H.; Huang, W.;Chen, X.*; Yu, K.*Photoluminescent Colloidal Nanohelices Self-Assembled from CdSe Magic-Size Clusters via Nanoplatelets.J. Phys. Chem. Lett.2019,10, 2794-2801.
6.Chen, X.; Chen, X.; Zhu, X.; Cai, B.; Fan, H.*; Zhang, X. Effect of Surface Topography of Hydroxyapatite on Human Osteosarcoma MG-63 Cell.J. Inorg. Mater. 2013, 28, 901-906.
7.Jiang, D.; Zhao, H.; Yang, Y.; Zhu, Y.;Chen, X.; Sun, J.; Yu, K.; Fan, H.; Zhang, X. Investigation of Luminescent Mechanism: N-rich Carbon Dots as Luminescence Centers in Fluorescent Hydroxyapatite Prepared Using a Typical Hydrothermal Process.J. Mater. Chem. B.2017,5, 3749-3757.
8.Zhu, Y.; Chen, S.; Zhao, H.; Yang, Y.;Chen, X.; Sun, J.; Fan, H.*; Zhang, X.PPy@MIL-100 Nanoparticles as a PH- and Near-IR-Irradiation Responsive Drug Carrier for Simultaneous Photothermal Therapy and Chemotherapy of Cancer Cells.ACS Appl. Mater. Interfaces2016,8,34209-34217.
9. Zuo, Y.; Xiao, W.;Chen, X.; Tang, Y.; Luo, H.; Fan, H.* Bottom-up approach to build osteon-like structure by cell-laden photocrosslinkable hydrogel. Chem, Commun. 2012, 48, 3170-3172.
10. Zhong, M.;Chen, X.; Fan, H.*; Zhang, X. Incorporation of Salmon Calcitonin-loaded Poly(lactideco-glycolide) (PLGA) Microspheres into Calcium Phosphate Bone Cement and the Biocompatibility Evaluation in Vitro.J. Bioact. Compat. Pol.2012, 27, 133-147.
联系方式
邮箱地址：xqchen@scu.edu.cn
办公地址：四川大学望江校区西五教
